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01.10.2024: Sebastian Glatt has been appointed as Professor of Systems Genetics at the University of Veterinary Medicine in Vienna effective from the 1st of October 2024. The distinguished geneticist and molecular biologist joins Vetmeduni from his previous position at the Małopolska Centre of Biotechnology (MCB) in Kraków to help advance research in the field of systems genetics, RNA diagnostics and therapy.

After 16 years abroad, Vienna native Sebastian Glatt is coming home. The newly appointed Professor of Systems Genetics at Vetmeduni brings with him an extensive network of contacts and a wealth of experience in RNA biochemistry and structural biology. He describes his new place of work as a “sweet spot” for his future plans, as his research is complementary to the veterinary field. To date, Sebastian Glatt has channelled his expertise into researching neurodegenerative diseases and cancer in humans. But his “RNA-centric view” will also be a useful addition to animal medicine, as ribonucleic acid is a fundamental molecule found in all living organisms. Glatt’s research is aimed at uncovering the molecular and structural mechanisms in tRNA biology that regulate the production of all proteins. Changes in these central molecules play an important role in the development of a variety of diseases.

View from the RNA perspective

After studying genetics and microbiology at the University of Vienna, Sebastian Glatt completed his doctorate in the pharmaceutical industry, specifically at Boehringer Ingelheim Austria, where he developed an awareness for clinically relevant research and project management. Five years later, in 2008, he moved to the European Molecular Biology Laboratory (EMBL) in Heidelberg on an interdisciplinary post-doctoral fellowship, joining the Structural and Computational Unit. In the following eight years, he made up for what he had missed while working in industry: the playful element of research as well as the opportunity to conduct research without restrictions, with sufficient time to solve complex problems, and with the ultimate goal of gaining fundamental scientific insights. In 2015, Sebastian Glatt moved to Kraków to take up a position at the Małopolska Centre of Biotechnology at Jagiellonian University, where he not only led his own independent Max Planck Research Group but also served as scientific director and helped to establish the National Centre for cryogenic Electron Microscopy at the SOLARIS National Synchotron Radiation Centre. In 2020, Glatt was awarded an ERC Consolidator Grant. Earlier this year, he was elected as a new member of the renowned European Molecular Biology Organization (EMBO).

In his teaching activities at Vetmeduni, Sebastian Glatt plans to focus on the basics of systems genetics, RNA diagnostics and therapy, especially where human medicine is slightly ahead of veterinary science. His focus will be on the role of specific RNA modifications for clinical interventions and their significance in clinical practice. In line with his belief that you can only truly understand something when you can also explain the connections, he expects to generate insights on both sides of the lecture hall.


Note:
A detailed portrait of Sebastian Glatt can be found in the next issue of VETMED Magazine.

Have you settled back into life in Vienna by now?
We are currently looking for a suitable place and for a primary school for my daughter, who is due to start school in September 2025.

What motivated your decision to accept the position at Vetmeduni?
Vetmeduni has an excellent international reputation, and Vienna has a very strong RNA and structural biology community. During my talks with the university, I was able to confirm my positive first impression of the university and of campus life, which made my decision after receiving the offer an easy one.

What are you looking forward to now following your arrival at Vetmeduni?
Getting to know as many of my new colleagues as possible and making interesting new contacts.

What will you miss about Kraków and the MCB?
The ambition and drive to catch up with history. Young people in Poland have the feeling that each single one of them can move the whole country forward.

What is especially important to you in teaching?
Our knowledge of genetics and molecular biology has grown enormously since I was a student, and we are just beginning to unravel and understand the most basic principles of the most complex cellular mechanisms. In the future, this molecular knowledge will have a much greater impact on diagnostic and therapeutic approaches in clinical practice, and we need to prepare students for these changes. Above all, I would like to pass on my passion and enthusiasm for research and teaching to the next generations.

 

Word Rap

The most difficult technical term that justifiably needs an abbreviation?
WARP – Durchlichtelektronenmikroskopiebilddatenentzerrungswerkzeug

What do you do when you get stuck in your research?
I talk to as many people as possible about it, because often thoughts only materialise when you put them into words.

Your ultimate motivational song?
“Best of You” by the Foo Fighters.

Team Coffee or Team Tea?
Team Coffee in the morning, Team Tea during the day.

Things that I always have in my work/lab cupboard…
Cap and winter coat for the cold room, 3D goggles, headphones.